There have been numerous questions that have generated serious doubt about the use of antimicrobial coatings on surfaces to combat infectious diseases that spread through touch. My first article published in the July 2020 edition of PCI magazine, titled “A Guide to Antimicrobial Coatings,” provided some basic information about the technology. This concise article is meant to educate users further and answer a few questions that were not covered earlier. In-depth technical details about antimicrobial coatings can be found in my book, Handbook of Antimicrobial Coatings.