This article examines some of the primary points to consider when scaling up
processes from laboratory equipment to production equipment.
What do manufacturers of milling equipment use as scaling factors, and what are their primary concerns with scale up? Equipment manufacturers calculate the amount of grinding energy required to achieve a specified level of particle size reduction and the resultant dispersion of the ground particles. This number is known as the specific energy requirement (Espec). However, several other variables are involved in the scale up, including the following.